Premature Ovarian Failure Treatment in New Delhi
Preserve remaining fertility with early intervention and egg preservation techniques. Open doors to biological children via customized IVF or donor options.
Key Facts
- Ovarian failure
- Before 40
- Low oestrogen
- Irregular periods
- Hormonal imbalance
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As an IVF and fertility specialist with over 10 years of experience, I, Dr. Mannan Gupta, often consult with young women who have just received a devastating diagnosis: Premature Ovarian Failure (POF), also known as Primary Ovarian Insufficiency (POI).
At my clinic in Delhi, I understand that learning your ovaries have stopped functioning before the age of 40 can feel like a profound loss—of your fertility, your sense of self, and your dreams of motherhood.
The first thing I want you to hear is that while this diagnosis is life-altering, it is not the end of your story. It is a complex condition that requires a dual approach: managing the health implications and, most importantly, navigating your path to parenthood.
My commitment is to guide you through this journey with medical expertise, deep compassion, and a clear-eyed view of the options that modern fertility science can offer.
Key Takeaways
- A Change in Function, Not Just Age: POF means the ovaries have stopped working properly in women under 40, affecting both periods and fertility.
- Health Implications: The loss of oestrogen has long-term health effects that need to be managed, including bone and heart health.
- Pregnancy is Possible: While natural conception is rare, options like donor egg IVF have exceptionally high success rates.
- Emotional Support is Crucial: This diagnosis carries a heavy emotional weight, and we are here to support you every step of the way.
What is Premature Ovarian Failure (POF)?
Premature Ovarian Failure, or Primary Ovarian Insufficiency (POI), is a condition where a woman’s ovaries stop functioning normally before the age of 40.
This means the ovaries are no longer releasing eggs regularly and are not producing enough of the hormone oestrogen.
It is crucial to understand that POF is not the same as early menopause. In menopause, periods stop completely.
In POF, about 5-10% of women may still have intermittent ovarian function and can occasionally get a period or even conceive. However, for most, it marks the end of their natural reproductive window.
Causes: Why Does This Happen?
In over 90% of cases, the exact cause of POF is unknown (idiopathic). However, for a small percentage, we can identify a specific reason:
- Genetic Conditions: Disorders like Turner Syndrome or Fragile X Syndrome can lead to POF.
- Autoimmune Disease: In some women, the body’s immune system mistakenly attacks its own ovarian tissue. This can be associated with thyroid disease or Addison’s disease.
- Medical Treatments (Iatrogenic): Chemotherapy or radiation for cancer treatment can damage the ovaries, leading to premature failure.
- Ovarian Surgery: Multiple surgeries on the ovaries, for conditions like endometriosis, can sometimes reduce ovarian tissue and lead to POF.
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Symptoms: Recognising the Signs
The symptoms of POF are essentially the symptoms of low oestrogen, similar to what women experience in menopause. They include:
- Irregular or Missed Periods: This is often the first and most noticeable sign.
- Hot Flushes and Night Sweats.
- Vaginal Dryness and Discomfort.
- Difficulty Sleeping and Mood Swings.
- Low Libido (Sex Drive).
- Infertility: The inability to get pregnant is the primary reason most women seek help and receive this diagnosis.
Diagnosis: Getting a Clear Answer
If POF is suspected, the diagnosis is confirmed through simple blood tests and a detailed history.
- Hormone Testing: We measure key hormone levels. In POF, the Follicle-Stimulating Hormone (FSH) level will be very high (typically >25-40 IU/L on two separate occasions) because the brain is working overtime trying to stimulate ovaries that are no longer responding. Oestrogen levels will be very low.
- AMH (Anti-Müllerian Hormone) Test: This blood test gives us an idea of the remaining egg reserve. In POF, the AMH level is usually undetectable or extremely low.
- Karyotyping and Genetic Screening: We often recommend these tests to check for underlying genetic causes.
Treatment: A Two-Fold Approach
Treating POF is about managing your immediate health and planning your future family.
1. Hormone Replacement Therapy (HRT)
This is not about fertility; it is about your long-term health. The loss of oestrogen at a young age significantly increases the risk of osteoporosis (thinning bones) and heart disease.
HRT replaces the hormones your body is no longer making, protecting you from these risks. It is a vital part of managing your overall well-being and is typically continued until the natural age of menopause (around 50-51).
2. Building Your Family: The Path to Parenthood
For most women with POF, conceiving with their own eggs is highly unlikely. The most effective and successful path to parenthood is through Donor Egg IVF.
- The Process: We use eggs from a young, healthy, and screened donor. These eggs are fertilised with your partner’s sperm in our IVF lab to create embryos. An embryo is then transferred into your uterus, which has been prepared with hormones to be receptive.
- The Success Rate: Donor egg IVF offers the highest success rates in all of fertility medicine, often with a 60-70% chance of pregnancy per transfer. It allows you to experience pregnancy, childbirth, and breastfeeding, and your partner is the biological father of the child.
Cost of Pregnancy Care in Delhi
The cost of managing POF involves two components: the diagnostic and health management aspect, and the fertility treatment aspect.
Service / Treatment | Approximate Cost in Delhi |
Hormonal Blood Tests (FSH, Oestrogen, AMH) | ₹3,000 – ₹6,000 |
Genetic Testing (Karyotype) | ₹4,000 – ₹7,000 |
Hormone Replacement Therapy (HRT) (Monthly) | ₹500 – ₹1,500 |
Donor Egg IVF Cycle | ₹2,00,000 – ₹3,50,000 |
Understanding the Cost Variation:
The cost of a donor egg IVF cycle can vary significantly. This depends on whether you use eggs from an anonymous donor from an egg bank or a known donor, and the specifics of the clinic’s programme.
We provide a fully transparent cost breakdown that covers donor screening, compensation, the IVF procedure, and your medication.
Contact us today to get the actual cost for your treatment and take the next step towards your parenthood journey!
Parenthood Starts with One Brave Conversation
Schedule a consultation with Dr. Mannan Gupta for honest answers and personalized fertility care.
Why Choose Dr Mannan IVF Centre?
Navigating a POF diagnosis requires a specialist who is not just a technician, but a compassionate guide.
- Holistic Management:
We focus on both your long-term health with HRT and your immediate family-building goals. - Expertise in Donor Egg IVF:
We run a highly successful and ethical donor egg programme, providing you with the best possible chance of achieving a healthy pregnancy. - Compassionate Counselling:
We understand that the decision to use donor eggs is a significant emotional step. Our team provides dedicated counselling to help you and your partner process these feelings and move forward with confidence. - Continuity of Care:
I will be with you from the initial diagnosis, through the emotional decision-making, to the joy of your first pregnancy scan.
Choosing the right doctor is one of the most important decisions you will make for your family.
- Continuity of Care:
As a specialist in both fertility and obstetrics, I offer a seamless transition from conception to cradle. I know your medical history intimately, which is invaluable for safety. - Patient-Centric Approach:
I believe in unhurried consultations. We take the time to listen to your concerns, explain medical concepts simply, and involve you in every decision. - Evidence-Based Safety:
We adhere strictly to international medical protocols. We do not prescribe unnecessary medicines or tests; every recommendation is backed by science. - Compassionate Environment:
Pregnancy can be emotional. My team and I strive to create a warm, supportive atmosphere where you feel cared for, not just treated.
The Emotional Journey of POF
A diagnosis of Premature Ovarian Failure can trigger a profound sense of grief. It is a loss of your expected biological future. It is okay to feel angry, sad, and overwhelmed.
We strongly encourage our patients to seek counselling. Acknowledging these feelings is the first step toward healing and opening your heart to a different, but equally beautiful, way of building your family.
Conclusion
A diagnosis of Premature Ovarian Failure is a challenging turn on your life’s path, but it is not a dead end. With proper health management through HRT and the incredible possibilities offered by donor egg IVF, your future can still be full of health, happiness, and the joy of motherhood.
At Dr Mannan IVF Centre in New Delhi, we are here to hold your hand, provide the highest level of medical care, and help you write the next chapter of your story.
You are not alone on this journey. Let us find your path forward together.
If you have been diagnosed with POF or are experiencing symptoms, you need specialist care. Book a consultation with Dr Mannan Gupta to discuss your health and your family-building options.
Frequently Asked Questions (FAQs)
1. Is there any way to reverse Premature Ovarian Failure?
Unfortunately, there is currently no proven medical treatment that can reverse POF or restore normal ovarian function. The focus of treatment is on managing the health consequences and using donor eggs for fertility.
2. Can I still have a baby that is genetically mine?
For the vast majority of women with POF, this is not possible as there are no viable eggs left. Donor egg IVF allows your partner to be the biological father, and you have the invaluable experience of carrying the pregnancy and giving birth.
3. Is HRT safe?
For young women with POF, HRT is not only safe but essential. You are simply replacing the hormones that your body should be producing at your age. The benefits for your bone and heart health far outweigh any risks.
4. How do you choose an egg donor?
Our egg donors are young, healthy women who undergo extensive medical, genetic, and psychological screening. We match donors to you based on physical characteristics to ensure the best possible resemblance. The process is completely anonymous and ethical.
5. What is the difference between POF and Diminished Ovarian Reserve (DOR)?
DOR is a decline in egg quantity, often age-related, but the woman still has regular cycles and produces oestrogen. POF is a more complete cessation of ovarian function, with irregular or absent cycles and low oestrogen levels. DOR can sometimes lead to POF.
