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IVF-ICSI Treatment in New Delhi

Inject single sperm directly into egg for high success in severe male infertility. Overcome sperm motility issues to create viable embryos and healthy babies.

Key Facts

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At Dr Mannan IVF Centre in New Delhi, I guide couples through the landscape of fertility treatments every day.

When we discuss In Vitro Fertilisation (IVF), one of the most powerful advancements we talk about is ICSI, which stands for Intracytoplasmic Sperm Injection.

For many couples, particularly those dealing with male factor infertility, ICSI is the breakthrough that makes parenthood possible.

In traditional IVF, tens of thousands of sperm are placed in a dish with an egg, with the hope that one will fertilise it. But what if the sperm can’t swim properly, or if there aren’t many of them? This is where ICSI comes in.

With over 10 years of experience, I’ve seen how this precise, targeted technique can give nature a helping hand.

My goal is to help you understand how this remarkable technology works and how it can be the key to your success story.

Key Takeaways
  • Precision Fertilisation:
    ICSI involves injecting a single, healthy sperm directly into an egg, bypassing many common barriers to fertilisation.
  • The Gold Standard for Male Infertility:
    It is the most effective treatment for issues like low sperm count, poor motility, or abnormal shape.
  • A Solution for Past Failures:
    ICSI is often used after a previous IVF cycle failed due to poor or no fertilisation.
  • Part of an IVF Cycle:
    ICSI is not a standalone treatment; it is an advanced fertilisation method used within an IVF cycle.

What is IVF with ICSI?

Imagine the fertilisation process under a powerful microscope. In a standard IVF cycle, eggs and sperm are mixed in a lab dish to fertilise on their own.

In an IVF-ICSI cycle, the process is more deliberate. Our expert embryologist selects a single, healthy-looking sperm and, using a microscopic needle, carefully injects it directly into the centre of the egg.

This technique overcomes many obstacles. It does not matter if the sperm has difficulty swimming or penetrating the egg’s outer layer. By placing it inside, we give it the best possible chance to create a viable embryo.

Who is the Ideal Candidate for ICSI?

ICSI has revolutionised our ability to treat many forms of infertility. I typically recommend it in the following situations:

  • Severe Male Factor Infertility: This is the most common reason. This includes:
    • Low Sperm Count (Oligospermia): Not enough sperm to achieve fertilisation naturally.
    • Poor Sperm Motility (Asthenospermia): The sperm do not swim well enough to reach the egg.
    • Abnormal Sperm Shape (Teratozoospermia): The sperm’s shape prevents them from penetrating the egg.
  • Surgically Retrieved Sperm: When sperm are retrieved directly from the testicles (via TESA or Micro-TESE) in cases of Azoospermia (zero sperm count), they are not mature enough to fertilise an egg on their own. ICSI is essential in these cases.
  • Previous IVF Fertilisation Failure: If a couple has undergone a conventional IVF cycle where few or no eggs were fertilised, ICSI is the logical next step to overcome this issue.
  • Use of Frozen Sperm: Sperm that have been previously frozen and thawed may have reduced motility. ICSI can help ensure fertilisation.
  • Unexplained Infertility: In some long-standing cases of unexplained infertility, ICSI is used to bypass any subtle, unidentified sperm-egg interaction problems.

Dr Mannan IVF Centre

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The IVF-ICSI Process: A Step-by-Step Guide

An IVF-ICSI cycle follows the same initial steps as a standard IVF cycle. The key difference happens in the lab after the eggs are retrieved.

  1. Ovarian Stimulation:
    The female partner takes hormone injections for 10-12 days to stimulate her ovaries to produce multiple mature eggs.
  2. Egg Retrieval:
    This is a short, minimally invasive procedure done under light sedation. We collect the mature eggs from the ovaries using a fine needle guided by ultrasound.
  3. Sperm Collection and Preparation:
    On the same day, the male partner provides a semen sample. The lab washes and prepares the sample to isolate the healthiest, most motile sperm.
  4. Intracytoplasmic Sperm Injection (ICSI):
    This is the crucial step. Our embryologist examines the eggs to identify the mature ones. Then, under a high-power microscope, a single sperm is picked up with a micro-needle and injected into each mature egg.
  5. Embryo Culture:
    The fertilised eggs, now embryos, are placed in an incubator where they grow for 3-5 days. We monitor them closely as they develop.
  6. Embryo Transfer:
    The best-quality embryo (or embryos) is transferred into the woman’s uterus in a simple, painless procedure.
  7. Pregnancy Test:
    About two weeks later, a blood test is done to check if implantation was successful.

Success Rates and Benefits

The primary benefit of ICSI is that it dramatically increases the chance of fertilisation when sperm quality is an issue.

In experienced hands, fertilisation rates with ICSI are typically around 70-80%. This means that for every 10 eggs injected, we can expect 7-8 to fertilise and become embryos.

This gives couples who previously had almost no chance of conceiving a biological child a very real opportunity to build their family.

Cost of IVF-ICSI Treatment in Delhi

ICSI is an advanced technique that requires specialised equipment and highly skilled embryologists. This adds a modest cost to a standard IVF cycle.

Procedure

Approximate Cost in Delhi

Standard IVF Cycle

₹1,25,000 – ₹1,75,000

ICSI Procedure (additional)

₹15,000 – ₹25,000

Total IVF-ICSI Cycle Cost

₹1,40,000 – ₹2,00,000

Understanding the Cost Variation:
The final cost of an IVF-ICSI cycle depends on the dose of hormonal medications required by the female partner, which varies from person to person.

The ICSI cost is a fixed addition for the specialised lab work. We provide a complete and transparent financial breakdown before your cycle begins.

Contact us today to learn more about the exact costs and start your journey towards parenthood!

Parenthood Starts with One Brave Conversation

Schedule a consultation with Dr. Mannan Gupta for honest answers and personalized fertility care.

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Why Choose Dr Mannan IVF Centre for ICSI?

The success of ICSI is almost entirely dependent on the skill of the embryologist and the quality of the IVF lab.

  • World-Class Embryology Team: Our embryologists are highly trained and have years of experience in the delicate art of ICSI. Their precision directly impacts your success.
  • Advanced Laboratory: We use state-of-the-art microscopes and micro-manipulators to ensure the procedure is performed with the utmost accuracy and safety.
  • Comprehensive Male Fertility Care: As a centre that also specialises in complex male infertility issues like Azoospermia, we have deep expertise in handling all types of sperm, including surgically retrieved samples.
  • Ethical and Evidence-Based Practice: We recommend ICSI only when it is medically indicated. We believe in providing the right treatment for the right reason, ensuring your care is both effective and cost-efficient.

Emotional Support Through Your Cycle

An IVF-ICSI cycle is a significant emotional and physical investment. The two-week wait after the embryo transfer can be particularly stressful.

We foster a supportive and empathetic environment. Our team is always available to answer your questions, offer reassurance, and provide the emotional support you need to navigate the ups and downs of the treatment process.

Conclusion

ICSI is more than just a medical acronym; for millions of couples, it is the key that unlocks the door to parenthood.

It represents the perfect synergy of medical science and human skill, bypassing nature’s hurdles with incredible precision.

At Dr Mannan IVF Centre in New Delhi, we are proud to offer this advanced technology with the expertise and compassion needed to turn your hopes into a healthy pregnancy.

Ready to explore your options with ICSI?
If you are struggling with male factor infertility or have had a previous failed IVF cycle, let’s talk. Book a consultation with me, Dr. Mannan Gupta, IVF Specialist in new delhi, to find out if IVF-ICSI is the right path for you.

Frequently Asked Questions (FAQs)

Not necessarily. If the sperm parameters are normal, conventional IVF has excellent success rates and allows for a more “natural” selection process in the lab. We recommend ICSI specifically when there is a clear medical reason to do so.

Yes. Decades of data and millions of babies born worldwide have shown that the rates of birth defects or developmental issues in ICSI babies are no different from those in the general population or babies born from conventional IVF.

While ICSI significantly increases the probability of fertilisation, it is not a 100% guarantee. In very rare cases, an egg may not fertilise or may be damaged during the process. However, a complete failure of fertilisation with ICSI is extremely uncommon.

The embryologist selects the sperm based on its morphology (shape) and motility (movement) under a high-power microscope. The goal is to choose a sperm that appears structurally normal and healthy.

Yes. When eggs are thawed after being frozen, their outer shell can harden slightly. ICSI is routinely used with thawed eggs to ensure the sperm can penetrate and fertilise them successfully.

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