Failed IVF Treatment in New Delhi
Analyze past cycles to refine protocols and boost embryo quality dramatically. Achieve breakthrough pregnancies with advanced techniques and expert guidance.
Key Facts
- After failed IVF cycles
- Used after 1–3 failures
- Identifies failure cause
- Embryo quality assessed
- Uterine receptivity evaluated
For any IVF / Fertility related query, concern or help, just call us
At Dr Mannan IVF Centre, some of the most emotionally exhausted patients I meet are those who have been through multiple failed IVF cycles.
A failed cycle is devastating. More than one can leave you feeling hopeless, questioning the process, your body, and your future.
I want you to hear this loud and clear: A failed IVF cycle is not your fault, and it is not necessarily the end of the road. It is a painful but powerful piece of information.
With over 10 years of experience as a fertility specialist in New Delhi.
I know that a failure tells us we need to dig deeper, investigate further, and change our strategy.
My specialty is taking on these complex cases, finding the missing pieces of the puzzle, and creating a new, more precise path forward.
Key Takeaways
- Failure is Information: A failed cycle provides critical clues about what to do differently next time.
- The Embryo is Key: The majority of IVF failures are due to chromosomal abnormalities in the embryo.
- The Uterus Matters: The receptivity of the uterine lining is the second most critical factor.
- A Fresh Look Helps: A second opinion from a specialist can often uncover underlying issues that were previously missed.
Understanding Why IVF Cycles Fail
When an IVF cycle is unsuccessful, it is typically for one of two reasons: either the embryo was not healthy enough to develop, or the uterus was not receptive enough for the embryo to implant.
This is often called Recurrent Implantation Failure (RIF). Our job is to figure out which factor—or combination of factors—is at play.
The Embryo Factor
It is a biological reality that not all embryos are created equal. Even embryos that look perfect in the lab can have internal chromosomal abnormalities (aneuploidy) that prevent them from implanting or developing correctly.
This is the single most common reason for IVF failure and miscarriage, and the risk increases with the age of the woman providing the eggs.
The Uterine Factor
The uterus must be a welcoming environment for the embryo. This “window of implantation” is a very specific time when the uterine lining (endometrium) is perfectly receptive. Problems that can affect this include:
- Anatomical Issues: Polyps, fibroids, a uterine septum, or scar tissue can physically prevent implantation.
- Inflammatory Conditions: Chronic endometritis (a low-grade infection of the uterine lining) or Adenomyosis can create a hostile, inflammatory environment.
- Displaced Window of Implantation: For some women, their receptive window is earlier or later than standard. Transferring a perfect embryo at the wrong time will result in failure.
Other Contributing Factors
Less common but still significant factors include sperm DNA fragmentation, underlying autoimmune conditions, or lifestyle factors like smoking and obesity.
A Second Opinion: Our Investigative Approach
When you come to my clinic in Delhi after a failed IVF cycle, we do not just repeat the same protocol. We launch a full investigation.
- Deep Dive into Your History: We meticulously review your previous cycle records. How did your ovaries respond? What did the embryos look like? What was the protocol used? This history is rich with clues.
- Advanced Uterine Assessment: We go beyond a basic ultrasound.
- 3D Ultrasound/MRI: To get a detailed look at the uterine structure.
- Hysteroscopy: A direct look inside the uterus to find subtle polyps, adhesions, or signs of inflammation.
- Endometrial Biopsy: To test for chronic endometritis.
- Assessing Endometrial Receptivity:
- ERA (Endometrial Receptivity Analysis): This test helps us pinpoint your personal “window of implantation” to ensure we transfer the embryo at the perfect time.
- Embryo Genetic Testing:
- PGT-A (Preimplantation Genetic Testing for Aneuploidy): This involves testing a small sample of cells from the embryo before transfer. It allows us to select only the chromosomally normal (euploid) embryos, dramatically increasing the chance of implantation and reducing miscarriage risk.
Dr Mannan IVF Centre
Experience world-class fertility care with Dr. Mannan Gupta at the Best IVF Centre in Delhi
Advanced Treatments for Recurrent IVF Failure
Once we have answers, we can build a new strategy.
Personalised IVF Protocols
Based on your previous response, we might change the type or dose of medication. For poor responders, we may use milder protocols. For others, we might use a “long down-regulation” protocol to suppress conditions like adenomyosis before stimulation.
Preimplantation Genetic Testing (PGT-A)
This is a game-changer for many couples. By ensuring we only transfer a chromosomally normal embryo, we eliminate the biggest cause of IVF failure.
Timed Embryo Transfer (Based on ERA)
If your receptive window is displaced, we adjust the embryo transfer day to match your unique biological clock.
Surgical Correction
If we find polyps, fibroids, or scar tissue, a simple hysteroscopic surgery can often restore the uterus to a receptive state.
Immunological and Adjuvant Therapies
In select cases, we may use medications like blood thinners or steroids to address underlying immunological issues that might be preventing implantation.
Cost of Investigating and Treating Failed IVF in Delhi
A second opinion and advanced treatments involve specialised tests and expertise. We believe in being fully transparent about these costs.
Test / Treatment | Approximate Cost in Delhi |
Second Opinion Consultation & File Review | ₹3,000 – ₹7,000 |
Diagnostic Hysteroscopy | ₹20,000 – ₹35,000 |
ERA Test | ₹40,000 – ₹60,000 |
IVF with PGT-A (per cycle) | ₹2,50,000 – ₹3,50,000 |
Understanding the Cost Variation:
These costs reflect the advanced technology and specialized expertise required for complex cases. For instance, PGT-A involves intricate lab work and precise genetic analysis.
Your total investment will depend on the specific investigations and treatments tailored to your unique situation.
We provide a clear, detailed financial breakdown before you commit to any path.
Ready to get a personalized cost estimate for your journey? Book a consultation today to receive a detailed financial plan designed for your specific needs.
Parenthood Starts with One Brave Conversation
Schedule a consultation with Dr. Mannan Gupta for honest answers and personalized fertility care.
Why Choose Dr Mannan IVF Centre?
Navigating recurrent IVF failure requires more than just a standard IVF clinic. It requires a specialist.
- A Focus on Complex Cases: My practice has a special focus on helping couples who have failed cycles elsewhere. I am passionate about finding solutions where others have not.
- Evidence-Based Approach: We do not throw a “kitchen sink” of unproven treatments at you. Every test and therapy we recommend is backed by scientific evidence.
- In-House Expertise: From advanced PGT-A in our lab to complex hysteroscopic surgeries, we have the comprehensive expertise needed under one roof.
- Empathy and Resilience: We understand the profound emotional toll of IVF failure. We are here not just to treat you, but to support you and rebuild your hope.
Emotional Support and Resilience
Repeated IVF failures can leave you emotionally drained and self-doubting. At our centre, we understand that healing is not only medical but emotional too.
We listen, explain, and support you at every step—so you never feel alone or blamed. With clarity, compassion, and the right plan, hope and confidence can return.
Conclusion: A New Chapter of Hope
Recurrent IVF failure is heartbreaking, but it does not have to be the end of your story. It should be the beginning of a new, more informed chapter.
By taking a step back, investigating deeply, and using the most advanced tools available, we can often change the outcome.
Your resilience has brought you this far; let our expertise guide you the rest of the way.
Are you ready for a fresh perspective?
Do not let past failures define your future. Book a second opinion with me, Dr. Mannan Gupta, and let us work together to write a new success story.
Frequently Asked Questions (FAQs)
1. After how many failed IVF cycles should I seek a second opinion?
While some couples choose to after just one failed cycle, it is highly recommended after two or three unsuccessful cycles, especially if you had good-quality embryos transferred.
2. Is PGT-A safe for the embryo?
Yes. The biopsy is performed by highly skilled embryologists on the part of the embryo that will become the placenta, not the baby itself. Large-scale studies have shown it to be a safe and effective procedure.
3. What if all my embryos are abnormal?
This is difficult news, but it is a definitive answer. It prevents you from undergoing a transfer that would have inevitably failed. This information allows us to have an honest discussion about next steps, which could include another IVF cycle or considering donor eggs.
4. Can lifestyle changes make a difference in my next cycle?
Absolutely. Optimising your weight, quitting smoking, improving your diet, and managing stress can improve both egg and sperm quality, which contributes to creating healthier embryos.
5. How do you decide which tests to do? I don't want to do unnecessary ones.
5. How do you decide which tests to do? I don’t want to do unnecessary ones.
This is a key part of our philosophy. We decide which tests are needed based on a careful review of your specific history. For example, if your cycles repeatedly failed despite having many “perfect-looking” blastocysts, we would strongly suspect an embryo issue and recommend PGT-A. We tailor the investigation to you.
